杰米（杰克•吉伦哈尔 Jake Gyllenhaal 饰）出身医药世家，舌灿莲花，热情似火，是电器行的金牌销售，不过由于桃花运太壮，以至于因为跟女同事在工作时间亲热，被老板开除。此后，他在辉瑞公司连番洗脑后，成为了一名医药销售代表。为了能打开区域市场，他摸清了某医院的底细，决定从主治医师斯坦下手。他用1千美元的支票，换取了一个实习生的身份，穿梭于诊室。某日，他偶然间邂逅了因帕金森症就诊的女患者玛姬（安妮•海瑟薇 Anne Hathaway 饰），并阴差阳错瞥见了她的乳房。正当花花公子以为占了便宜时，却被玛姬抡包打伤，甚至还拍了照片。为了讨回声誉，他利用关系要到了对方号码，并约她面谈。没想到这次约会，却让两人陷入了匪夷所思的亲密关系之中，令他难以自拔。正当杰米因伟哥成为销售红人时，玛姬的病患却每况愈下……《爱情与灵药》虽然口碑平平，却依然有不少打动人的地方。电影结局处杰克所扮演的男主角Jamine的一段表白和画外音就格外让人感动，情人节来临之际，一起来看看吧。

I'm full of shit, OK? I am knowingly full of shit. Because I have never cared about anybody or anything in my entire life, and the thing is everybody have accepted that...like "That's just Jamine."  And then you... Jesus ... you didn't see me that way. I have never known anyone who actually believed that I was enough until I met you, and then you made me believing too. So unfortunately, I need you and you need me... Let's just say... that in some alternate universe, there's a couple just like us. Only she is healthy, and he is perfect. And their world is about how much money they are spending on vacation, who's in bad mood that day, or whether or not they're guilty about having a cleaning lady. I don't wanna be those people. I want us. You. This.
我是个混蛋。真的，人人都知道我是个混蛋。因为我这辈子从来没有真正在乎过什么人什么事儿，而且所有人都觉得习以为常了，他们都说：“杰米就是这样子的。”然而我遇到了你……天啊……只有你，不会这么看待我。在认识你之前，从来没有人相信我是可以依靠的一个人；也是你，才让我自己相信了自己。所以很不幸，我需要你，你也需要我。打个比方，在某个异度的时空里，有一对跟咱俩差不多的小情侣。只不过那里的他们俩，女的健康，男的完美。他们所有的问题只不过是度假花多少钱啦，谁今儿心情不好啦，雇个清洁工要不要有罪恶感什么的。我不要成为那些安逸的人。我只要我和你。只要你。只要我们在一起。

I used to worry a lot about who I'll be when I grow up. Like how much money I'd make, or someday I become some big deal. Sometimes the things you want the most doesn't happen, and sometimes the thing you never expect happen does. Like giving up my job in Chicago and everything, and deciding to stay and apply for med school. I don't know - you meet thousands of people and none of them really touch you. And then you meet that one person and your life is changed. Forever.
我以前总是担心自己长大后会怎么样。赚多少钱。会不会有一天出人头地。有时候你最是盼星星盼月亮的事儿就是不会发生，可意想不到的那些却自然而然地来了。比方放弃在芝加哥的工作，放弃一切，决定留下来攻读医科学校。我说不清楚为什么，你遇见过千百个人，而他们只不过是匆匆过客；接着你就邂逅了那么一个人，改变了你的生命直到永远。